Radionuclide venography (RNV) of the pel via and lower extremity veins using ttmTc-albu

via and lower extremity veins using ttmTc-albu. mm microspheres was performed in 53 patients with pulmonary emboli or venous disease. In 25 patients who underwent both contrast and RNV studies, there were no false-positive studies and one false-negative. In this series the accu racy of RNV exceeded that of Doppler alone. When the results of these two methods were combined, false-negative studies were elimi nated. Over half the patients with pulmonary emboli and clinically normal lower extremities had abnormal RNV studies. The exact method of thrombus localization is not known but both mechanical and electrostatic factors may be in volved. RNV has been shown to be a safe, accu rate, and easily performed examination which is particularly useful in evaluating patients with pulmonary emboli.